If your first child had hypospadias, you may be worried about your next pregnancy - this is understandable! While there's a slightly increased risk in subsequent male children (about 10-15% vs 0.3% in general population), many families go on to have healthy babies. You CAN take steps to reduce risk, but complete prevention isn't always possible since the exact cause is unknown.
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What is Hypospadias?
Family Risk:
| Situation | Risk |
|---|---|
| General population | 0.3-0.4% (1 in 250-300 boys) |
| Father has hypospadias | ~8% risk in son |
| One brother affected | ~12% risk in next male child |
| Two brothers affected | Higher risk |
Important: Even with family history, most subsequent male babies will NOT have hypospadias!
1. Achieve Healthy Weight (BMI 18.5-24.9)
2. Start Folic Acid Early
3. Quit Smoking Completely
4. Stop Alcohol Consumption
5. Eat a Balanced Diet
6. Regular Medical Checkups
1. Avoid Endocrine Disruptors
2. Don't Use Unnecessary Hormones
3. Don't Delay Medical Care
4. Avoid Certain Medications
5. Don't Stress Excessively
First Trimester (Critical Period):
Throughout Pregnancy:
Remember: Despite all precautions:
Before Pregnancy:
During Pregnancy:
Know that:
A: If you had one son with hypospadias, the risk for the next male child is about 10-15% (compared to 0.3% in general population). This means 85-90% of your subsequent male babies will NOT have hypospadias. The risk increases if the father also had it or if multiple family members are affected.
A: Unfortunately, complete prevention isn't possible since the exact cause is unknown and genetics play a role. However, you can reduce risk by: maintaining healthy weight, taking folic acid, quitting smoking and alcohol, eating well, and avoiding environmental toxins. Even then, some cases occur despite all precautions.
A: Genetic testing may be recommended if there's strong family history (multiple affected members) or if other birth defects occurred together. Discuss with a genetic counselor who can advise based on your specific situation. For isolated hypospadias in one child, testing may not be necessary.
A: It's important to know that hypospadias is NOT your fault! While some factors (smoking, alcohol, certain medications) may increase risk, many cases occur without any identified cause. Don't blame yourself - focus on healthy habits for the next pregnancy.
A: Gender selection for this reason is not recommended or easily done. Remember, even with family history, most male babies (85-90%) will be healthy. The condition is also treatable with excellent outcomes. Discuss your concerns with a genetic counselor who can provide perspective.
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This article was reviewed by a pediatrician. Last updated: January 2025
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